Medically reviewed by Stuart Wasser, MD, Medical Director • View Profile • Editorial process
Polysubstance Addiction
Expert Medical Care.
When you're struggling with addiction to multiple substances, treatment becomes more complex—and more critical. At Integrity Treatment Partners in Baldwin, NY, our medical team specializes in managing complex withdrawals and cross-addiction patterns safely.
Why Polysubstance Use Is Dangerous
Mixing substances dramatically increases overdose risk. Different drugs interact unpredictably, and withdrawal from multiple substances requires careful medical sequencing. Never attempt to detox from multiple substances without medical supervision.
Common Combinations We Treat
Opioids + Benzodiazepines
The deadliest combination—both depress breathing.
Alcohol + Opioids
Extremely common and extremely dangerous.
Stimulants + Opioids
"Speedballing" puts extreme strain on the heart.
Alcohol + Benzodiazepines
Both affect GABA receptors—withdrawal can be life-threatening.
Our Treatment Protocol
Medical Assessment: We evaluate all substances used, quantities, and timeline to create a safe withdrawal sequence.
Sequenced Detox: We prioritize dangerous withdrawals first (benzos, alcohol) while managing other symptoms with medication.
Cross-Addiction Education: We teach you how addictions reinforce each other and how to prevent substituting one drug for another.
Proudly Serving Nassau County Communities
Integrity Treatment Partners provides outpatient addiction treatment and mental health services to residents throughout Nassau County and surrounding areas. We proudly serve the following communities from our centrally located facility in Baldwin, NY: